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However with effective January 5, 2026 several states have moved to aggressively recalibrate their tobacco taxes

Therefore, we aim to test a secondary hypothesis that baseline nicotine metabolite ratio (NMR) will moderate the experimental treatment effect, such that the benefit of dose titration will be greater in those participants who are rapid metabolizers of nicotine, and the final titrated dose they reach will be higher on average than the slow metabolizers

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ABC News' Liz Neporent contributed to this report.

He's mad that I did that movie and he got sucked into watching it." I was like, "Are you going to give me a ticket, based on that