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These genes have previously shown sensitivity in response to DNA methylation changes 41

Those who specifically use snuff are 50% more at risk of developing buccal mucosa and gingival-related cancers than those who do not

Menthol also interacts with nicotine in the brain to enhance the addictiveness of nicotine, making it harder for people to quit smoking, explained Rachel Grana Mayne, Ph.D., a program director in NCI's Tobacco Control Research Branch

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