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( ii ) when mortality probabilities for NS increase or decrease by 10%, life expectancy changes by 1.2y ( 1.6%) compared with the base case in all subpopulations (Additional File 1, Supplementary Table 2)

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The MR analyses indicated causal associations between smoking and the risk of obstructive chronic bronchitis, cancer of the bronchus, emphysema, peripheral vascular disease, chronic airway obstruction, pneumococcal pneumonia and type 2 diabetes

Supreme Court Justice Ruth Bader Ginsburg was treated for early-stage pancreatic cancer in 2009, 10 years after she had colorectal cancer