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"Lorillard and Reynolds American near merger"

Circulation 121 , 23312378 (2010)

Mortality A large US study constituting a high level of evidence pooling two longitudinal studies found no increase in mortality overall or due to smoking-related cancers or CVD in never smoking SLT-product users compared with never-smoking never-SLT-product users [43]

The findings revealed that heavy smokers (20 pack-years) who quit smoking experienced a significantly lower CVD risk within five years compared to current heavy smokers, with a hazard ratio of 0.61, thus confirming the cardiovascular benefits of smoking cessation seen in other research

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It took several decades to determine the problems associated with tobacco use