Racing Thoughts And Disjointed Speech Racing thoughts and disjointed speech are psychological indicators of amphetamine dependence because a 400% increase of noradrenaline enhances alertness and arousal within 45 minutes of drug-taking, leading to [7]: Disorganised thinking and speech in up to 55% of daily amphetamine users, including continual loud outbursts, abrupt switching of topics, and the slurring of words [30] Users appear alert, agitated, and over-reactive, with rapid incessant speech and unpredictable behaviour, including talking to themselves or arguing/yelling at others without an explanation [17] Racing thoughts and disjointed speech caused by amphetamine misuse typically subside within 1 month, although 30% experience symptoms for 1 - 6 months, and 4% of cases develop into Schizophrenia [32]

Studies of nicotine medications indicate that the risks of nicotine without tobacco combustion are low compared to cigarette smoking, but are still of concern in people with cardiovascular disease 15,18,43
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