To minimize this potential bias from unmeasured confounding, analyses accounted for baseline differences between cohorts (eg, age), differences among current, former, and never smokers, temporal trends (eg, declining smoking rate, increasing BMI), birth cohort effects, and factors that could influence both smoking cessation and CVD risk, including sociodemographic factors and known CVD risk factors, which were time-updated
Carbon Monoxide (CO) A poisonous gas that reduces oxygen supply in the blood, forcing the heart to work harder and increasing the risk of cardiovascular disease
By Age About 5 out of every 100 adults aged 1824 years (5.3%) and nearly 13 out of every 100 adults aged 2544 years (12.6%) reported smoking
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