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Patients typically experience progressive dyspnea, especially with exertion, and may have minimal cough or sputum production compared to chronic bronchitis

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Numerous neuroscientific studies confirmed the prominent role of the amygdala in emotional processing in a number of sensory modalities [30,31,52] especially threat and fear [53,54]

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Following our ongoing interest in developing green protocols obeying to circular economy principles 23,24 we report herein, unprecedented in the literature, a protocol that exploits cigarettes filters as source of Levulinic acid avoiding the strong acidic conditions and extendable at an industrial level

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