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Physical Effects One of the most immediate physical effects of cigarette smoking is increased heart rate and blood pressure

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Critchlow V, Liebelt RA, Bar-Sela M, Mountcastle W, Lipscomb HS (1963)

As Peter Hajek, a professor at Queen Mary University of London, put it, Regulators need to watch out for intended consequences of overzealous regulation, such as stifling such developments or making e-cigarettes more expensive and less attractive to smokers