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Based on the extent to which the included studies adjusted for potential confounders, we categorised them as best-adjusted and others

Real-life responses The qualitative nature of the study meant it explored individual responses as well as the mean trend

Larger cigars typically contain more tobacco and can deliver more nicotine over time, which may increase perceived strength

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Oral steroids, or steroid pills, also suppress inflammation by de-activating the switches that turn on immune system reactions