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[29] A true breakthrough came in 1948, when the British physiologist Richard Doll published the first major studies that proved that smoking could cause serious health damage

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TNF- is a pro-inflammatory cytokine which is reported to activate other cytokines such as Il-8 and IL-6 [31]

For example, cadmium in tobacco decreases the levels of selenium and zinc, an important mineral needed in the production of an antioxidantsuperoxide dismutase

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I hate to sound like a pushy mom, but Im telling you this with my editors hat on, not my mothers hat on