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The high levels of disease-related biomarkers in smokers were not surprising, Rezk-Hanna noted, since research has shown that cigarette smoking and other forms of combusted tobacco expose users to high levels of chemicals that cause inflammation and oxidative stress

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A controlled clinical study by Cooper and Haney (2009) found that joints actually produced higher plasma THC levels and stronger subjective intoxication ratings than blunts smoked with the same amount of cannabis

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