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[15] Claiming that filtered cigarettes literally "filtered out" much of the harmful tar and carcinogenic particles found in regular cigarettes, tobacco companies promoted "relative product safety" in order to convince smokers to continue smoking

Blistering and photosensitivity improve with age, while poikiloderma and skin atrophy persist.3 Around 10% of patients with KS can develop malignant skin tumors,1,11 such as squamous cell carcinoma, after 45 years of age.5 The mechanism underlying carcinogenesis may be related to low levels of transforming growth factor and increased Wnt signaling, both of which have been described in humans and mice with KS.12,13 The use of sunscreen and protective clothing is essential to minimize the risk of carcinogenesis in these patients, especially in countries with high levels of solar radiation, such as Peru.3,13 Involvement of the mucosa, especially the oral mucosa (85%), is frequent

This is compared to 2011 rates, where about 1.5% of high school students and 0.6% of middle school students reported current vape use

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