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24,36,44 Importantly, varenicline does not increase the risk of adverse neuropsychiatric events as compared to other agents or placebo (per the EAGLES trial), 24,36 and a black box warning for it has been removed

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Additionally, hyperbaric oxygen therapy (HBOT) has been suggested as a potential adjunctive therapy for PD

Figure 2 Table 3 lists all the models and the new parameters in the order of inclusion