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Thus, in non-tumor HPV infected cells, TS exposure promotes functional p53 activity, which is abrogated by E6 oncoprotein, leading to increased DNA damage and cancer initiation [101]

Datura stramonium , or thorn-apple, already had a following in the US, but its British popularity began as an alternative to similar treatments learnt from Indian medicine during the East India Companys control over the subcontinent