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[18] The degree to which teens are using e-cigarettes in ways the manufacturers did not intend, such as increasing the nicotine delivery, is unknown, [107] as is the extent to which e-cigarette use may lead to addiction or substance dependence in young people

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[7] It became the number one cigarette sold in the world by 1966, a position it held until 1972 when Marlboro overtook the brand

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