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Tobacco abuse liability is increased by the presence of pyrazines, which can compensate for the poor reinforcing effects of nicotine alone by acting on central nervous system receptors and enhancing the addictive potential of cigarettes

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The agency said the handful of seizure reports often lack information about the brand of e-cigarette or whether users had a medical condition that might have contributed

It can also be added to other Gainsborough products to dilute them