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Epigenetic modifications are a part of normal, healthy human functioning, but when the addition or removal of marks goes awry because of lifestyle choices like smoking, it can lead to devastating health issues

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Abstract Purpose of review: To provide an overview of the underlying neurobiology of tobacco smoking in schizophrenia, and implications for treatment of this comorbidity

Since a median weight gain of 1.8 kg was observed at 1 year after smoking cessation, we divided the participants into high and low-weight gain groups