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This includes bisphenol A (BPA), an endocrine-disrupting chemical used in cardboard and paper coating 34 , and Per- and Polyfluoroakyl substances (PFAS), which are common in impregnated paper for food packaging and coated woods and are known as forever chemicals because of their extraordinary persistence in the environment with potential ecotoxicological effects 35
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The FDA specifies a maximum recommended dose of 10 mg per day for elderly patients to prevent clinically significant accumulation
In subsequent experiments, the effects of CSC on VEGF and HIF-1 mRNA expression in HMEECs were evaluated
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