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One thing that is known about electronic cigarettes: they've become a serious business in the United States

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Australia banned smoking on all of its flights from 1996

In 2008, the World Health Organization (WHO) urged marketers to remove claims that e-cigarettes are a safe and effective way to quit smoking because no scientific evidence was available to support those claims

Snuff: Finely ground tobacco, sometimes flavored, for nasal use

Moreover, this study is not an individual patient meta-analysis, where effect pooling can be performed using a statistical model that incorporates a uniform set of covariates