betel nut and tobacco New report reveals high prevalence of betel, chewing in Western Pacific Humans Were Buzzing On Psychoactive

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As a result: Cortisol levels remain elevated Inflammation increases Blood pressure rises Immune function weakens Sleep quality declines Over time, this constant stress state contributes to cardiovascular disease, metabolic disorders, mental health challenges, and reduced lifespan

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Diagnosis of IBS by the Rome IV criteria IBS was diagnosed if the patient reported recurrent abdominal pain occurring on average at least one day per week in the last three months that was associated with two or more of the following criteria: abdominal pain related to defecation

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