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Underutilization of smoking cessation treatment The American Heart Association/American College of Cardiology 2016 guidelines for the management of patients with PAD who smoke recommend using pharmacotherapy and/or referral to a smoking cessation program (54)

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Tobacco contains the chemical nicotine, which is an addictive substance

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Tobacco smoke contains over 7,000 chemicals and acts in a number of ways to cause CVD

The study included people who have previous smoking history pipes, currently pipe smokers as well as non-pipe smoking