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Sa1788 Tobacco Toxin NNK (4-[Methylnitrosamino]-1-[3-Pyridyl]-1-Butanone) Mediates Zymogen Activation in Murine and Human Pancreatic Acini

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In our WCSE model, mitochondria showed fragmented morphology but maintained membrane potential and had lower ROS levels, indicating controlled remodeling rather than dysfunction