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This not only directly leads to reduced local oral defense, but also damages a variety of immune populations including CD3 cells, CD4 cells, B lymphocytes, and macrophages, allowing for the invasion of pathogens (Singh et al., 2012) have indicated that consumption of BQ is strongly associated with HPV, Candida infection, tuberculosis, dengue fever, malaria, typhoid fever, HIV/AIDS, and other infectious diseases