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Bergstrm J, Preber H
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Smoking and reproduction: gene damage to human gametes and embryos
Retrieved 27 June 2021
Mitochondrial biogenesis is tightly regulated by transcriptional coactivators of the Peroxisome Proliferator-Activated Receptor (PPAR) Gamma (PPARG), Coactivator 1 (PPARGC1) family, respectively PPARGC1 Alpha (PPARGC1A), PPARGC1 Beta (PPARGC1B) and PPARG Coactivator-Related 1 (PPRC1), and their downstream transcription factors such as Nuclear Respiratory Factor 1 (NRF1), Nuclear Respiratory Factor 2 (NRF2) and Transcription Factor A, Mitochondrial (TFAM) 26,27,28
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