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Selected enriched canonical pathways are given in Table 1 and include interferon signaling, liver X receptor (LXR)/retinoid X receptor (RXR) activation, glucocorticoid receptor signaling, p38 mitogen-activated protein kinase (MAPK) signaling, IL13 signaling pathway, Toll like receptor signaling, peroxisome proliferator-activated receptors (PPAR) signaling, aryl hydrocarbon receptor (AHR) signaling, IL17 signaling, and airway pathology in chronic obstructive pulmonary disease (COPD)

Treatments include oral hygiene, mouthwash for tonsil stones, saltwater gargles, manual removal, or medical procedures

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