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In some circumstances, such as their use by non-smoking adolescents and young adults, their adverse effects clearly warrant concern

Theres an emerging body of novel interventions and strategies, such as increasing the age of sale of tobacco to 21, including e-cigarettes, and prohibiting the sale of flavored tobacco, which are percolating at the local level, King said

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This could potentially counteract some negative effects on the large airways, although more additional research is needed to confirm these findings

(Reuters Health contributed to this story)