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Trends in ENDS use among high school students increased from 1.5% in 2011 to a staggering 27.5% by 2019 for any use, and from 20% in 2017 to 34.2% in 2019 for frequent use

(2001) Stratton K, Shetty P, Wallace R, et al., editors

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This is especially true in patients who have been using drugs like meth or cocaine, which reduces appetite and causes people to lose large amounts of weight