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Analyses stratified the associations between EC and respiratory symptoms by combustible smoking status and showed that EC use was associated with significantly higher odds of developing respiratory symptoms among all smoking history groups: though the odds ratios of EC use were attenuated among never-smoking youth, they remained statistically significant

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In their final state they are lighter in colour than their surroundings (loss of melanocytes), less often hyperpigmented (dark-skinned people)

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