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Key Takeaways The original photo was published by The Cut on August 25, 2016, taken outside Affleck's home in Pacific Palisades The meme's power comes from authentic celebrity vulnerability, not manufactured relatability Affleck has personally acknowledged the meme but expressed concern about its impact on his children The image has revived multiple times 2020, 2023, 2025 each time finding new cultural resonance It represents a broader shift in meme culture toward empathy and solidarity rather than mockery The 2025 Sunset Tower photo proves the format is effectively immortal

Extracellular vesicles are involved in oxidative stress and mitochondrial homeostasis in pulmonary arterial hypertension

10.1016/j.chest.2019.08.2182 156 TaylorR

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Effect sizes, however, vary substantially within and across studies