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JAK are a part of the JAK/STAT pathway, and this signaling is continuously activated, resulting in the elevated level of MMPs and apoptotic chondrocytes in RA synovial joints (130)

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Chest X-ray was un remarkable Diagnosis and treatment Based on the clinical presentation and laboratory findings a diagnosis of pernicious anaemia due to vitamin B12 deficiency was made

Subdermal application overcomes this barrier and directly reaches the deeper layers of the skin, resulting in higher absorption and efficacy