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The results of SURPASS-6 further support the role of Tirzepatide in treatment of individuals with type 2 on insulin and obesity. The primary goal of the trial was to determine if tirzepatide was as safe and effective as fast-acting insulin in lowering A1C over 52 weeks

People on semaglutide lost around 13% of their body weight on average, while those taking the placebo lost around 3% on average

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This imbalanced agonism is a deliberate design feature and contributes to its unique clinical profile