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It is unnecessary

Because sepsis rapidly changes the microenvironment and endothelial cells are one of the cell types that first sense the changes caused by sepsis and undergo extensive molecular adaptations (83), further research into the renal vascular EG could help physicians diagnose sepsis as early as possible, thereby providing the opportunity for early intervention

These compounds exhibit various biological activities, including anti-inflammatory, antibacterial, antioxidant, analgesic, and anticancer effects, and are widely used in medicine, cosmetics, food additives, and aromatherapy

24 This could be due to subjective recording of atrophic scarring or may represent a subset of patients who are vulnerable to this scarring