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doi: 10.3389/fcell.2020.602574

Table of Contents Obesity is the second most common cause of preventable death, associated with the risk of developing inflammatory components, directly and indirectly, related to cardiovascular disease, diabetes mellitus, respiratory problems, psychological issues, hypertension, obstructive sleep apnea, cancer, and hyperlipidemia

Implications Beyond GLP-1 The successful development of orforglipron as a small-molecule agonist of a class B GPCR has opened new possibilities across the entire class

The drugs were also linked to fewer overdoses, hospitalizations, and drug-related deaths among people already living with addiction

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