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For women with confirmed B12 deficiency due to malabsorption or pernicious anaemia, intramuscular hydroxocobalamin is the first-line treatment in the UK

NAC can interact with certain medications like nitrates

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Preclinical studies have shown KPV significantly reduces the severity of intestinal inflammation, decreases pro-inflammatory cytokine activity, and supports intestinal barrier repair

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The prevention and/or early treatment of accompanying physical comorbidities may, per s, may also modify the DE course