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Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model

Pickart and Margolina's 2018 review in the International Journal of Molecular Sciences catalogues the wider picture, including clinical work in which a GHK-Cu facial cream applied over 12 weeks improved skin density, firmness, and the look of fine lines, and GHK-Cu is one disclosure-worthy case, which is covered in the disclosures section below

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Glutathione for Vascular and Cellular Brightening: Glutathione reduces oxidative cellular stress around the eye area, shifting melanin synthesis toward the lighter Phaeomelanin pathway and providing antioxidant protection that addresses the oxidative component of both surface pigmentation and the vascular visibility that makes discolouration in this area more pronounced

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