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This research theorized that nutrients presented in their naturally grown forms supply cofacters that make them more bioavailable, biologically active, and therefore more effective than nutrients that are isolated

Here we show morphine-induced constipation is mediated by a neural circuit from glutamatergic neurons in the paraventricular nucleus of hypothalamus (PVN Glu ) to acetylcholinergic neurons in the dorsal motor nucleus of the vagus (DMV Ach ), and subsequently to the small intestine in mice

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This study also received funding from Cooperation Projects of Sichuan Credit Pharmaceutical CO., Ltd