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Differences were evaluated by Students t test for two groups, one-way analysis of variance for multiple groups, and parametric generalized linear model with random effects for tumor growth

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Weight loss effects vary by population, with clinical trials showing up to 21-22% mean weight loss in obesity trials (non-diabetes patients) and lower percentages in type 2 diabetes patients, depending on dose

doi: 10.1016/j.autrev.2009.02.020